Table 4.
Stratification of the prevalence of advanced colorectal neoplasia by risk tier
| Risk tier | Derivation set | Validation set | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Number (%) | ACN (%) (95% CI) | Number (95% CI) | ACN (%) (95% CI) | OR (95% CI) | Neoplasia (%) (95% CI) | OR (95% CI) | CRC (%) (95% CI) | OR (95% CI) | |
| AR (0–2) | 541 (56.6) | 10 (1.8) (0.7–3.0) | 743 (61.9) | 15 (2.0) (1.0–3.0) | – | 167 (22.5) (19.5–25.5) | – | 3 (0.4) (0–0.9) | – |
| HR (≥3) | 414 (43.4) | 29 (7.0) (4.5–9.5) | 458 (38.1) | 30 (6.6) (4.3–8.8) | 3.4 (1.8–6.4) | 216 (47.2) (42.6–51.8) | 3.1 (2.4–4.0) | 7 (1.5) (0.4–2.7) | 3.8 (1.0–14.9) |
| Total | 955 (100) | 39 (4.1) (2.8–5.1) | 1201 (100) | 45 (3.7) (2.7–4.8) | – | 383 (31.9) (29.3–34.5) | – | 10 (0.8) (0.3–1.3) | – |
ACN Advanced colorectal neoplasia, OR Odds ratio, CI Confidence interval. AR Average risk, HR High risk