Table 5.
Mean Levonadifloxacin Cmax and AUC on Day 5 Following Intravenous WCK 771 and Oral WCK 2349 Administered Twice Daily to Healthy Indian Subjects
| Dose | WCK 771 | WCK 2349 | ||
|---|---|---|---|---|
| Cmax (µg/mL) | AUC(0–12) µg·h/mL | Cmax (µg/mL) | AUC(0–12) µg·h/mL | |
| 600 mg, q12h | 26.3 | 142.97 | 14.81 | 91.11 |
| 800 mg, q12h | 32.04 | 195.96 | 20.56 | 120.10 |
| 1000 mg, q12h | 38.54 | 213.3 | 29.68 | 186.36 |
| 1200 mg, q12h | 41.26 | 263.15 | 33.78 | 225.21 |
Note: Data From: Niu J, Ivaturi V, Gobburu J, Chugh R, Bhatia A. Pharmacokinetics of levonadifloxacin administered as intravenous WCK 771 and oral WCK 2349 in healthy Indian male adults. Abstract A-032, 55th ICAAC; 2015.44