Table 3.

The Univariate and Multivariate Cox Analyses of OS

Variables	Univariate Analysis		Multivariate Analysis
HR (95% CI)	P-value	HR (95% CI)	P-value
Gender(Male/Female)	0.822(0.548–1.232)	0.342	0.998(0.630–1.583)	0.994
Age(<60/≥60 year)	2.308(1.441–3.698)	0.001	2.071(1.195–3.588)	0.009
Tumor location	0.966(0.844–1.106)	0.619	0.967(0.792–1.181)	0.743
Tumor size(<5/≥5 cm)	1.693(1.060–2.704)	0.027	1.339(0.797–2.249)	0.270
Extent of resection(Total/Not total)	1.729(1.136–2.633)	0.011	1.566(0.940–2.610)	0.085
WHO grade(WHOI+II/WHO III+IV)	5.863(3.567–9.636)	<0.001	5.301(2.912–9.650)	<0.001
Intracranial Infection(Yes/No)	0.952(0.594–1.524)	0.837	0.935(0.537–1.629)	0.813
KPS(≥70/<70)	1.604(1.066–2.413)	0.023	1.059(0.647–1.733)	0.820
Radiotherapy/Chemotherapy (Yes/No)	1.197(0.803–1.782)	0.377	1.374(0.846–2.231)	0.199
F-NLR-AGR		<0.001		<0.001
Score 0	1(reference)	1(reference)
Score 1	2.119(0.958–4.685)	0.064	1.136(0.468–2.759)	0.779
Score 2	5.110(2.383–10.957)	<0.001	3.622(1.554–8.445)	0.003
Score 3	8.144(3.600–18.422)	<0.001	3.738(1.497–9.332)	0.005

Abbreviations: KPS, Karnofsky performance status; F-NLR-AGR, combination of fibrinogen, albumin to globulin ratio and neutrophil to lymphocyte ratio.