Table 2.

Liposomal Formulations Stability. Five Independent Batches of Liposome Were Stored and Sealed in Sterile Vials at 4°C for 30 and 60 Days. Thereafter, Samples were Taken Out from the vials for Characterization Including Particle Size, and Entrapment Efficiency Evaluation. The stability of liposomal ZYZ-802 Was Assessed in Line with the Original Values Before Storage

Time Period (Day)	DP-ZYZ-802		SA-ZYZ-802
Vesicle Diameter (nm)	Entrapping Efficiency (%)	Vesicle Diameter (nm)	Entrapping Efficiency (%)
0	189.0±5.4	30.5±2.0	205.7±5.9	28.6±1.3
30	193.7±4.7	28.9±1.8	252.3±47.4	26.1±1.3*
60	196.1±6.4	27.8±2.0	266.2±47.9*	23.1±0.9*

Notes: *P<0.05 vs 0 Day, calculated by two-tailed Student’s t-test