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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Mol Oral Microbiol. 2019 Feb 7;34(2):27–38. doi: 10.1111/omi.12252

FIGURE 2.

FIGURE 2

NADPH oxidase derived ROS differentially modulate neutrophil effector responses. NADPH oxidase deficient (oxidase null) neutrophils are deficient in killing of catalase positive microorganisms and Aspergillus species. NET production is also compromised in response to select stimuli. ROS deficiency enhances degranulation, cytokine and chemokine generation that might lead to persistent inflammation by recruitment of other immune cells and/or their differential polarization. NADPH, nicotinamide adenine dinucleotide phosphate; NET, neutrophil extracellular traps; ROS, reactive oxygen species