Table 2.
Association of rs2464196 and rs1169310 genotypes with AFP levels in healthy Chinese subjects.
| rs2464196 | rs1169310 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| R 2 | β | 95% CI | SE | P | R 2 | β | 95% CI | SE | P | |
| Model 1 | 0.017 | -0.078 | -0.114, -0.043 | 0.018 | 0.000018∗ | 0.013 | -0.070 | -0.106, -0.034 | 0.018 | 0.000139∗ |
| Model 2 | 0.028 | -0.080 | -0.115, -0.044 | 0.018 | 0.000012∗ | 0.024 | -0.072 | -0.108, -0.036 | 0.018 | 0.000087∗ |
| Model 3 | 0.066 | -0.072 | -0.108, -0.037 | 0.018 | 0.000056∗ | 0.063 | -0.065 | -0.100, -0.029 | 0.018 | 0.000339∗ |
Model 1: no adjustment; model 2: adjusted for age, gender, and BMI; model 3: adjusted for age, gender, BMI, blood pressure, LDL, HDL, TC, lnAST, lnALT, lnTG, lnGGT, lnCRP, FPG, and fatty liver. β represents the unstandardized beta coefficients (β) for the effects of HNF1A polymorphisms on the AFP levels. P values for the associations of the rs2464196 or rs1169310 genotypes with the AFP level. ∗P values that passed Bonferroni correction (P < 0.0167).