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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Neurotoxicology. 2019 Sep 18;75:136–147. doi: 10.1016/j.neuro.2019.09.003

Table 1.

Summary of Experimental Design and Behavioral Tasks Utilized in the Pilot Study (Experiment 1) and Multi-Dose Study (Experiment 2)

Doses mg/kg/day Method of Dosing Duration of Dosing OF L/D Box EPM Running Wheel
Experiment 1 0.1 Food Treat GD 9 - PND 21 (Dam) Not Included PND 110 – 120 PND 185 – 192 PND 160 – 170
NCSU Ethanol Vehicle (10-min test) (5-min test) (63 hours)
Experiment 2 0.1 Gavage GD 9 – PND 21 (Dam) PND 90 & PND 150 – 155 PND 155 – 160 Not Included
NTP/NIEHS 25 Sesame Oil Vehicle PND 22 – 90 (Offspring) PND 145 – 150 (5-min test) (5-min test)
250 (30-min test)