Table 2.
Risk groups for salvage radiotherapy
| Risk group | Factors |
| Low-risk | PSA < 0.6 ng |
| PSA-DT > 12 mo | |
| Gleason score ≤ 7 (ISUP 1,2) | |
| pT2 pN0 | |
| IBR > 18 mo | |
| Negative margins | |
| Intermediate risk | PSA = 0.6 to < 1 ng |
| PSA-DT 6-12 mo | |
| Gleason score 7 (ISUP 3) | |
| pT2-T3a pN0 or pNx | |
| IBR > 18 mo | |
| Positive margins | |
| High-risk | PSA ≥ 1 ng |
| PSA-DT < 6 mo | |
| Gleason score 8-10 (ISUP 4,5) | |
| pT3b pN0 or pNx | |
| IBR < 18 mo | |
| Positive margins |
ADT: Androgen deprivation therapy; PSA: Prostate-specific antigen; PSA-DT: Prostate-specific antigen doubling time; IBR: Interval to biochemical recurrence; ISUP: International Society of Urological Patheology.