Table 13.

Updated analgesic dosing recommendations

Species	Agent	Dose (mg/kg)	Route	Frequency
Mouse	Buprenorphine	0.1-0.5	SC	4-6 h
	Buprenorphine SRzp	0.6	SC	48 h
	Tramadol	80	SC	24 h
	Carprofen	5	SC	12 h
		20	SC	24 h
	Meloxicam	5-10	SC	8-12 h
	Ketoprofen	20	SC	24 h
Rats	Buprenorphine	0.05-0.0.1	SC	6-8 h
		0.5-0.6	PO	24 h
	Buprenorphine SRzp	1.2	SC	48 h
	Tramadol	20-40	PO	24 h
		5	SC	24 h
	Carprofen	5	SC	24 h
	Meloxicam	1	SC	12-24 h
	Ketoprofen	5	SC	24 h
Guinea pig	Buprenorphine	0.05	SC	6 h
	Buprenorphine SRzp,ag	0.3-0.48	SC	48 h
	Carprofen	4	SC	12-24 h
	Meloxicam	0.2	SC	12-24 h

Modified from Flecknell 2018.⁶¹

SR = sustained release; # - provided in food treat, should be observed ingesting

zP = manufactured by Zoopharm, Windsor, CO; ag= manufactured by Animalgesics Laboratories, Millersville, MD.

Note: caution should be taken with higher doses of NSAIDs. Multimodal analgesia recommended to allow effective use of lower doses.