Table 2. HR (95% CI) for the Incidence of Type 2 Diabetes According to Body Size Phenotype and Metabolic Stability.
Variable | Total | Events | Follow-up duration, person-yr | Incidence rate, /1,000 person-yr | HR (95% CI) | |||
---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | |||||
Stable MHNW | 2,377,219 | 21,312 | 9,258,446 | 2.30 | 1 | 1 | 1 | 1 |
Unstable MHNW | 305,924 | 15,071 | 1,170,674 | 12.87 | 5.60 (5.48–5.72) | 4.33 (4.24–4.43) | 4.20 (4.41–4.29) | 3.23 (3.16–3.30) |
Stable MHO | 545,546 | 9,274 | 2,121,322 | 4.37 | 1.90 (1.85–1.95) | 1.77 (1.73–1.81) | 1.77 (1.72–1.81) | 1.81 (1.76–1.85) |
Unstable MHO | 250,825 | 15,693 | 951,933 | 16.49 | 7.19 (7.04–7.34) | 6.10 (5.97–6.22) | 5.96 (5.84–6.08) | 4.67 (4.58–4.77) |
Model 1: not adjusted; Model 2: adjusted for age and sex; Model 3: adjusted for model 2 plus smoking, alcohol consumption, regular exercise, and family history of type 2 diabetes; Model 4: adjusted for model 3 plus mean fasting plasma glucose.
HR, hazard ratio; CI, confidence interval; MHNW, metabolically healthy normal weight; MHO, metabolically healthy obese.