Table 1.
Total | miR-362-5p expression | p | Sema3A expression | p | ||||
---|---|---|---|---|---|---|---|---|
(n = 150) | Negative/weak (n = 72) | Moderate/strong (n = 78) | Negative/weak (n = 52) | Moderate (n = 53) | Strong (n = 45) | |||
Age | ||||||||
≤50 y | 46 | 22 | 24 | 0.9774 | 13 | 19 | 14 | 0.4822 |
>50 y | 104 | 50 | 54 | 39 | 34 | 31 | ||
Grade | ||||||||
I+II | 74 | 37 | 37 | 0.6507 | 27 | 24 | 23 | 0.6301 |
III | 65 | 35 | 30 | 19 | 25 | 21 | ||
T stage | ||||||||
T1 | 39 | 24 | 15 | 0.0661 | 9 | 15 | 15 | 0.1875 |
T2 | 90 | 41 | 49 | 32 | 32 | 26 | ||
T3 | 17 | 5 | 12 | 9 | 6 | 2 | ||
N stage | ||||||||
N0 | 78 | 39 | 39 | 0.8396 | 24 | 27 | 27 | 0.098 |
N1 | 38 | 18 | 20 | 14 | 12 | 12 | ||
N2 | 19 | 8 | 11 | 9 | 5 | 5 | ||
N3 | 13 | 5 | 8 | 4 | 9 | 0 | ||
AJCC stage | ||||||||
I | 24 | 16 | 8 | 0.0703 | 4 | 11 | 9 | 0.0407 |
II | 82 | 38 | 44 | 28 | 25 | 29 | ||
III | 38 | 14 | 24 | 17 | 16 | 5 | ||
HER-2 | ||||||||
Negative | 89 | 26 | 63 | <0.0001 | 34 | 31 | 24 | 0.3932 |
Positive | 54 | 43 | 11 | 15 | 20 | 19 | ||
ER | ||||||||
Negative | 78 | 35 | 43 | 0.4765 | 32 | 25 | 21 | 0.2583 |
Positive | 71 | 36 | 35 | 20 | 28 | 23 | ||
PR | ||||||||
Negative | 91 | 43 | 48 | 0.9981 | 34 | 32 | 25 | 0.4566 |
Positive | 55 | 26 | 29 | 16 | 19 | 20 | ||
Types | ||||||||
ER+ and/or PR+ | 79 | 37 | 42 | 0.0002 | 25 | 30 | 24 | 0.2278 |
HER-2+/ER−/PR− | 27 | 21 | 6 | 6 | 10 | 11 | ||
HER-2−/ER−/PR− | 35 | 9 | 26 | 17 | 10 | 8 |