Table 2.
Endometrial epithelium thickness (μm) after subchronic oral exposure to CdCl2 or 17β-estradiol (E2) exposure and 90- and 180-day postexposure periods in comparison to controls.
| Groups | Endometrial epithelium thickness (μm) | ||||||
|---|---|---|---|---|---|---|---|
| Pure control | 0.09 mgCd/kg | 0.9 mgCd/kg | 1.8 mgCd/kg | 4.5 mgCd/kg | Oil control | Positive control | |
| A—90-day exposure | 19.2 ± 2.2 | 27.0 ± 3.1a,c | 21.7 ± 3.6c | 20.1 ± 3.1c | 24.5 ± 6.3c | 21.9 ± 3.3 | 36.4 ± 2.5b |
| B—90-day postexposure period | 21.8 ± 4.3 | 21.9 ± 1.9c | 19.4 ± 2.1c | 17.9 ± 2.1c | 19.1 ± 2.9c | 21.80 ± 1.7 | 34.8 ± 2.5b |
| C—180-day postexposure period | 21.7 ± 1.7 | 19.6 ± 1.3c | 18.9 ± 2.5c | 17.1 ± 1.7a,b,c | 16.5 ± 1.6a,b,c | 22.5 ± 2.1 | 33.8 ± 4.1b |
All values are expressed as mean ± SD. ap ≤ 0.05, significantly different from pure control animals. bp ≤ 0.0, significantly different from oil control. cp ≤ 0.05, significantly different from positive control.