Table 2.
Routine laboratory parameters of studied groups
| Parameter | HCC (n = 22) | Cirrhosis (n = 22) | P-value |
|---|---|---|---|
| ALT (U/l) | 89.14 ±86.36 | 27.59 ±12.71 | 0.002* |
| AST (U/l) | 154.14 ±112.44 | 55.59 ±26.66 | 0.001* |
| Albumin (g/dl) | 2.07 ±0.48 | 2.32 ±0.43 | 0.076 |
| Total bilirubin (mg/dl) | 6.17 ±5.29 | 3.80 ±6.44 | 0.189 |
| Direct bilirubin (mg/dl) | 4.02 ±3.98 | 2.32 ±4.63 | 0.199 |
| Alkaline phosphatase (U/l) | 130.95 ±66.30 | 93.95 ±72.56 | 0.085 |
| GGT (U/l) | 80.64 ±50.73 | 49.27 ±47.75 | 0.041* |
| BUN (mg/dl) | 72.41 ±39.15 | 56.91 ±35.50 | 0.176 |
| Creatinine (mg/dl) | 1.20 ±0.38 | 1.33 ±0.54 | 0.357 |
| AFP | 276.21 ±252.92 | 69.93 ±43.82 | 0.002* |
| PT (s) | 19.01 ±3.14 | 17.31 ±4.21 | 0.137 |
| INR | 1.64 ±0.23 | 1.45 ±0.35 | 0.038* |
| Hb (g/dl) | 10.49 ±1.43 | 10.46 ±1.50 | 0.951 |
| RBC (× 106 cells/mm3) | 3.12 ±0.60 | 3.26 ±0.58 | 0.416 |
| WBC (× 103 cells/mm3) | 12.21 ±8.19 | 8.18 ±3.59 | 0.041* |
| Platelets (× 103 cells/mm3) | 117.41 ±46.16 | 118.50 ±62.83 | 0.948 |
Data are expressed as mean ± standard deviation
*
statistically significant at p < 0.05, n – number
HCC – hepatocellular carcinoma, ALT – alanine transaminase, AST – aspartate transaminase, GGT – gamma-glutamyl transpeptidase, BUN – blood urea nitrogen, AFP – alpha-fetoprotein, PT – prothrombin time, INR – international normalized ratio, Hb – hemoglobin, RBC – red blood cell count, WBC – white blood cell count.