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. 2019 Dec 27;9(4):2045894019895414. doi: 10.1177/2045894019895414

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 1. — (a) Plasma levels and difference of MMP-7 in PH subgroups. MMP-7 levels in PAH were higher than in controls (p < 0.0001) but lower than in the other disease groups (p < 0.0081). (b) ROC curve of MMP-7 levels in PAH versus other groups. AUC: area under the curve; CTEPH: chronic thromboembolic PH; HFpEF-PH: PH due to HF with preserved EF; HFrEF-PH: PH due to HF with reduced EF; HF-NON-PH: HF without PH; MMP-7: matrix metalloproteinase-7, PAH: pulmonary arterial hypertension; ** indicates p value <0.01; ****indicates p-value < 0.0001.