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. 2019 Dec 10;5(12):1929–1936. doi: 10.1021/acscentsci.9b00870

Figure 4.

Figure 4

Complete eradication of S. aureus inoculated in the mouse femoral canal by PEGDMA-Oligo-Vanco coating. (a) IVIS images of mouse femurs injected with 40 CFU Xen-29 S. aureus and inserted with IM pins with PEGDMA-Oligo-Vanco or PEGDMA-Oligo coatings at 2, 7, 14, and 21 days. (b) Quantification of longitudinal bioluminescence signals of mouse femurs injected with 40 CFU Xen-29 S. aureus and inserted with the different hydrogel-coated pins at 2, 7, 14, and 21 days (n = 14). (c) S. aureus recovery from 21 day explanted pins (n = 11). Error bars represent standard deviations. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001 (two-way ANOVA for part b; Student’s t-test for part c).