Table 2.
Clinical and hemodynamic parameters of the 259 analyzed patients differentiated by aetiology.
| All patients | Group 1 | Group 2 | Group 3 | Group 4 | pa | |
|---|---|---|---|---|---|---|
| Number | 259 | 103 | 26 | 80 | 50 | – |
| Age (years) | 65 ± 13 | 60 ± 13 | 70 ± 13 | 68 ± 10 | 67 ± 12 | <0.001 |
| 6-minute-walk distance (m) | 344 ± 113 | 375 ± 112 | 325 ± 113 | 302 ± 86 | 332 ± 128 | 0.002 |
| Ntpro-BNP (pg/ml) | 1620 ± 1940 | 1447 ± 1825 | 1661 ± 1236 | 1631 ± 2026 | 1948 ± 2292 | 0.555 |
| TAPSE (mm) | 18.3 ± 4.9 | 18.4 ± 4.6 | 17.4 ± 4.9 | 18.3 ± 4.9 | 18.3 ± 5.5 | 0.859 |
| DLCO (% pred) | 49 ± 22 | 57 ± 19 | 54 ± 19 | 33 ± 18 | 56 ± 18 | <0.001 |
| Mean PAP Dx (mmHg) | 42 ± 11 | 46 ± 12 | 39 ± 10 | 37 ± 9 | 42 ± 9 | <0.001 |
| PAWP Dx (mmHg) | 10 ± 6 | 9 ± 4 | 20 ± 5 | 9 ± 5 | 9 ± 4 | <0.001 |
| PVR Dx (WU) | 7.3 ± 4.3 | 8.8 ± 5.0 | 4.1 ± 2.5 | 6.2 ± 3.2 | 7.8 ± 3.6 | <0.001 |
| CO Dx (l/min) | 4.9 ± 1.5 | 4.8 ± 1.6 | 5.2 ± 1.7 | 5.0 ± 1.4 | 4.9. ± 1.5 | 0.608 |
| Innocor-PBF (l/min) | 4.3 ± 1.3 | 4.1 ± 1.3 | 4.6. ± 1.4 | 4.2 ± 1.3 | 4.4 ± 1.2 | 0.372 |
| Innocor-PBF (l/min/m2) | 2.3 ± 0.6 | 2.2 ± 0.6 | 2.6 ± 0.8 | 2.3 ± 0.6 | 2.4 ± 0.6 | 0.033 |
Note: Results are provided as mean ± standard deviation.
CO: cardiac output; DLCO: diffusion capacity of the lung for carbon monoxide; Dx: diagnosis; PAP: pulmonary arterial pressure; PAWP: pulmonary arterial wedge pressure; PBF: pulmonary blood flow; PVR: pulmonary vascular resistance; TAPSE: tricuspid annular plane systolic excursion; WU: Wood unit.
a
Difference between the groups (t-test for continuous variables).