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. 2019 Dec 23;58(1):e01384-19. doi: 10.1128/JCM.01384-19

TABLE 4.

Final results and profiles obtained with confirmatory serological assays for detecting HTLV-1/2 antibodies in 111 serum samples that yielded WB-inconclusive results and were tested by LIA

Group and WB result for each samplea WB profile LIA resultb LIA profile Final result
G1
    Indeterminate GD21, p24 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24, p26, p28, p32, p36, p53 HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate p19, p26, p28, p53 Negative p19-I/II Negative
    Indeterminate GD21,c p24c HTLV p19-I/II, p24-I/II, gp46-I/II, gp21-I/II HTLV
    Indeterminate GD21, p24 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    Indeterminate p24, rgp46-II HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp46-II HTLV-2
    Indeterminate GD21 Indeterminate gp21-I/II Indeterminate
    Indeterminate p24 Indeterminate p19-I/II, p24-I/II Indeterminate
    Indeterminate GD21, rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p19 HTLV-1 p19-I/II, gp21-I/II, p19-I HTLV-1
    Indeterminate p24, p36, rgp46-II HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21 Indeterminate gp21-I/II Indeterminate
    Indeterminate p19, p26, p28, p53 Negative p19-I/II Negative
    Indeterminate p24c Indeterminate gp21-I/II Indeterminate
    HTLV GD21,c p19,c p24 HTLV-1 p19-I/II, p24-I/II, gp21-I/II, p19-I HTLV-1
    Indeterminate p19 Negative p19-I/II, p19-I Negative
    Indeterminate p19, p24 Negative p24-I/II Negative
    Indeterminate GD21,c p24c Indeterminate gp21-I/II Indeterminate
    HTLV GD21, p19, p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, gp21, rgp46-II HTLV-2 p19-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24 HTLV p19-I/II, p24-I/II, gp46,-I/II, gp21-I/II HTLV
    Indeterminate GD21, rgp46-II, rgp46-I Negative No bands Negative
    Indeterminate GD21, p24,c rgp46-I HTLV-1 p19-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate GD21c Negative p19-I/II Negative
    HTLV GD21, p19, p24, p26, p28, p32 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24 HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate p19,c rgp46-I HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate p24,c rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    HTLV GD21, p19, p24, p26, p32, p36, p53 HTLV p19-I/II, p24-I/II, gp46-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24 HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p19 HTLV p19-I/II, gp46-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21,c p24 HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24, p32, p36 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate p24,c rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate p24, rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    Indeterminate p24c Negative No bands Negative
    Indeterminate GD21 Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21, rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46II HTLV-2
    Indeterminate p19 Negative p19-I/II Negative
    Indeterminate GD21, p24,c rgp46-Ic Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21, p19, p26 HTLV p19-I/II, gp46-I/II, gp21-I/II HTLV
    Indeterminate GD21, rgp46-II Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21, p24,c rgp46-Ic Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21, rgp46-I Indeterminate gp21-I/II Indeterminate
    HTLV GD21, p19, p24 HTLV-2 p19-I/II, p24-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, rgp46-II, rgp46-Ic HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate p24 Indeterminate p19-I/II, p24-I/II Indeterminate
    Indeterminate p19 Negative p19-I/II Negative
    Indeterminate p19c HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate GD21, rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21,c p19 HTLV-2 p19-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    HTLV GD21, p19, p24, p26, p32, p36 HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I, gp46-I HTLV-1
    Indeterminate GD21, p24 HTLV-2 p19-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    HTLV GD21, p19, p24 HTLV-1 p19-I/II, p24-I/II, gp21-I/II, p19-I HTLV-1
    Indeterminate p19 Negative p19-I/II Negative
    HTLV GD21, p19, p24 HTLV-1 p19-I/II, p24-I/II, gp21-I/II, p19-I HTLV-1
G2
    Indeterminate rgp46-I HTLV-1 p24-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate p24, rgp46-II HTLV-2 p24-I/II, gp46-I/II, gp21-I/II, gp46-I,c gp46-II HTLV-2
    HTLV GD21, p19, p24, p26,c p28,c p32,c p36c HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I, gp46-I HTLV-1
    Indeterminate GD21c Negative No bands Negative
    Indeterminate rgp46-Ic HTLV-1 gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate GD21,c rgp46-I HTLV-1 gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate GD21, p19c Indeterminate gp21-I/II Indeterminate
    Indeterminate p24, rgp46-II HTLV-2 gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate rgp46-II HTLV-2 p19-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21c HTLV p19-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24 HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate GD21 Negative No bands Negative
    Indeterminate GD21, p19 HTLV p19-I/II, p24-I/II, gp21-I/II HTLV
    Indeterminate p24, rgp46-II HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21c Indeterminate gp21-I/II Indeterminate
    Indeterminate p24 HTLV-2 gp46-I/II, gp21-I/II, gp46IIc HTLV-2
    Indeterminate GD21, p24 HTLV-2 p19-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate p19, p24, rgp46-II HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate rgp46-II HTLV-2 p19-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate rgp46-II HTLV-2 p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21, p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-II HTLV-2
    Indeterminate GD21,c p19c HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I,c gp46-I HTLV-1
    HTLV GD21,c p19,c p24 HTLV-2 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-IIc HTLV-2
G3
    HTLV GD21, p19, p24, p26,c p28,c p36c HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I, gp46-I HTLV-1
    HTLV GD21, p19, p24, p26,c p28,c p32,c p36,c gp46c HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    HTLV GD21,c p19, p24c HTLV p19-I/II, p24-I/II, gp46-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24, p26c, p28c, p36, gp46 HTLV p19-I/II, p24-I/II, gp46-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24, p26, p28, p32, p36, gp46, p53 HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I HTLV-1
    HTLV GD21, p19, p24, p26, p28, p32, p36 HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I HTLV-1
    Indeterminate GD21,c p19c HTLV p19-I/II, gp46-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24c HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I HTLV-1
    Indeterminate GD21, rgp46-II HTLV p19-I/II, gp21-I/II HTLV
    HTLV GD21, p19, p24,c p26, p28, p32, p36 HTLV-1 p19-I/II, p24-I/II, gp46-I/II, gp21-I/II, p19-I, gp46-I HTLV-1
    Indeterminate GD21, rgp46-I HTLV-1 p19-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate GD21, p19 HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate GD21c Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21 Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21 HTLV-1 gp46-I/II, gp21-I/II, gp46-I HTLV-1
    Indeterminate GD21 Negative No bands Negative
    Indeterminate p24c Negative No bands Negative
    Indeterminate rgp46-IIc Negative No bands Negative
    Indeterminate GD21, rgp46-I HTLV-1 p19-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
    HTLV GD21, p19, p24 HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate GD21 HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate GD21, rgp46-IIc HTLV p19-I/II, gp21-I/II HTLV
    Indeterminate GD21 Indeterminate gp21-I/II Indeterminate
    Indeterminate GD21, p19 HTLV p19-I/II, gp46-I/II, gp21-I/II HTLV
    Indeterminate p19, rgp46-I HTLV-1 p19-I/II, gp46-I/II, gp21-I/II, gp46-I HTLV-1
a

WB, Western blot (HTLV Blot 2.4; MP Biomedicals).

b

LIA, line immunoassay (INNO-LIA HTLV-I/II; Fujirebio).

c

Faint bands.