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. 2019 Dec 23;10:2891. doi: 10.3389/fimmu.2019.02891

Table 2.

(A) Pre-transplant characteristics of patients who died in the first trimester after heart transplantation vs. alive patients. (B) Logistic regression multivariate analysis of factors associated with mortality in the first trimester after heart transplantation.

(A) Pre-transplant characteristics Dead N = 23 Alive N = 128 P-value
Variable N/median %/IQR N/median %/IQR
Sex (female) 8 (34.8%) 20 (15.6%) 0.030
Age 52 42.3–61.0 51 39.0–58.5 N.S.
Body mass index 23.7 20.7–27.9 24.5 22.0–26.6 N.S.
IgA aB2GP1 positive and B2A-CIC positive 8 (34.8%) 11 (8.6%) <0.001
IgA aB2GP1 positive and B2A-CIC negative 5 (21.7%) 23 (18%) N.S.
Blood type
  Group 0 7 (30.4%) 61 (47.7%) N.S.
  Group A 15 (65.2%) 48 (37.5%) 0.013
  Group B 1 (4.3%) 14 (10.9%) N.S.
  Group AB 0 (0%) 5 (3.9%) N.S.
Rh positive 21 (91.3%) 107 (83.6%) N.S.
Other pathologies and risk factors
  Renal dysfunction 5 (21.7%) 23 (18%) N.S.
  HTA antecedents 5 (21.7%) 38 (29.7%) N.S.
  Diabetes 3 (13%) 29 (22.7%) N.S.
  Dyslipidemia 8 (34.8%) 41 (32%) N.S.
  Hyperuricemia 1 (4.3%) 17 (13.3%) N.S.
  Hyperbilirubinemia 9 (39.1%) 25 (19.5%) N.S.
  ALT/AST High levels 3 (13%) 34 (26.6%) N.S.
  Active smoker 7 (30.4%) 28 (21.9%) N.S.
  Ex-smoker 5 (21.7%) 36 (28.1%) N.S.
  No-smoking 11 (47.8%) 64 (50%) N.S.
  Patients with thrombotic antecedents 1 (4.3%) 6 (5.8%) N.S.
  Previously anticoagulated 15 (65.2%) 69 (53.9%) N.S.
Other vascular diseases
  Thrombosis A/V 1 (4.3%) 8 (6.3%) N.S.
  Thrombophlebitis 0 (0%) 2 (1.6%) N.S.
Ethnicity Caucasian 22 (95.7%) 123 (96.1%) N.S.
Ethnicity: others 1 (4.3%) 5 (3.9%) N.S.
(B) Multivariate analysis Univariate Multivariate
Variable OR 95% CI OR OR 95% CI OR P-value
B2A-CIC positive 5.67 1.97–16.33 6.13 1.93–19.40 0.002
Sex (female) 2.88 1.08–7.67 4.18 1.35–12.94 0.013
Blood type: Group A 3.13 1.23–7.92 4.05 1.44–11.43 0.008

IQR, interquartile range; N.S., not significant.