Table 3.

(A) Pre-transplant characteristics of patients who suffer thrombotic events in the first trimester after heart transplant vs. those without these events. (B) Logistic regression multivariate analysis of pre-transplant factors associated with incidence of thrombotic events in the first 3 months after heart transplantation.

(A) Pre-transplant characteristics	Patients with events N = 18		Patients without events N = 133		P-value
Variable	N/median	%/IQR	N/median	%/IQR
Sex (female)	3	(16.7%)	25	(18.8%)	N.S.
Age	50.5	40.0–58.0	52	39.0–59.0	N.S.
Body mass index	25.5	20.9–29.2	24.4	22.1–26.4	N.S.
IgA aB2GP1 + and B2A-CIC positive	7	(38.9%)	12	(9%)	<0.001
IgA aB2GP1 + and B2A-CIC negative	5	(27.8%)	23	(17.3%)	N.S.
Blood type
Group 0	9	(50%)	59	(44.4%)	N.S.
Group A	7	(38.9%)	56	(42.1%)	N.S.
Group B	1	(5.6%)	14	(10.5%)	N.S.
Group AB	1	(5.6%)	4	(3%)	N.S.
Rh positive	16	(88.9%)	112	(84.2%)	N.S.
Pathologies and risk factors
Renal dysfunction	2	(11.1%)	26	(19.5%)	N.S.
HTA antecedents	5	(27.8%)	38	(28.6%)	N.S.
Diabetes	2	(11.1%)	30	(22.6%)	N.S.
Dyslipidemia	7	(38.9%)	42	(31.6%)	N.S.
Hyperuricemia	1	(5.6%)	17	(12.8%)	N.S.
Hyperbilirubinemia	1	(5.6%)	33	(24.8%)	N.S.
ALT/AST High levels	7	(38.9%)	30	(22.6%)	N.S.
Active smoker	8	(44.4%)	27	(20.3%)	0.023
Ex-smoker	4	(22.2%)	37	(27.8%)	N.S.
No-smoking	6	(33.3%)	69	(51.9%)	N.S.
Patients with thrombotic antecedents	1	(5.6%)	6	(4.5%)	N.S.
Previously anticoagulated	9	(50%)	75	(56.4%)	N.S.
Other vascular diseases
Thrombosis A/V	2	(11.1%)	7	(5.3%)	N.S.
Thrombophlebitis	0		2	(1.5%)	N.S.
Ethnicity Caucasian	16	(88.9%)	129	(97%)	N.S.
Ethnicity: others	2	(11.1%)	4	(3%)	N.S.
(B) Multivariate analysis	Univariate		Multivariate
Variable	OR	95% CI OR	OR	95% CI OR	P-value
B2A-CIC positive	6.42	2.10–19.63	6.13	1.93–19.40	0.002
Active smoker	3.14	1.13–8.72	4.18	1.35–12.94	0.013

IQR, interquartile range; N.S., not significant.