2.
Inducers and suppressors of ferroptosis
| Inducer | Suppressor | ||||||
| System Xc- inhibitor | GPXs inhibitor | GSH Sythesis inhibitor | Ferritinophagy activator | Others | Iron chelator | Antioxidant | |
¶ RSL3: RAS-selective-lethal compound 3; † BSO: buthionine-(S, R)-sulfoximine; ‡ FAC: ferric ammonium citrate; § DFOM: desferrioxamine mesylate; ∫CPX: 8-Cyclopentyl-1,3-dimethylxanthine;
 BHT: butylated hydroxytoluene;
 HO-1: heme oxygenase-1.
| |||||||
| Erastin9 | RSL3¶9 | Statins48 | DpdtC99 | Dihydroartemisinin92 | Deferoxamine35 | Ferrostatin-1100 | |
| Sulfasalazine9 | DPI79 | BSO†44 | FAC‡101 | Artemisinin87 | DFOM§35 | Liproxstatin-1100 | |
| Sorafenib91 | DPI109 | Altretamine35 | CN-A and PEITC95 | Dp44mT85 | α-tocopherol102 | ||
| Glutamate9 | FIN5649 | PEBP1103 | 2,2-BP9 | Erythropoietin104 | |||
| Lanperisone38 | ML16038 | Ardisiacripsin B103 | CPX∫105 | Trolox38 | |||
| SRS13-4538 | Acetaminophen35 | BHT
 44
|
|||||
HO-1
 106
|
Cycloheximide38 | ||||||
| Aminooxyacetic acid38 | |||||||
| β–mercaptoethanol107 | |||||||
| XJB-5-131108 | |||||||
| JP4-039108 | |||||||
| Zileuton35 | |||||||
| Baicalein107 | |||||||