2.
Genes alterations | TPS ≥ 1% | TPS < 1% | P | TPS ≥ 50% | TPS < 50% | P |
*P< 0.05 was considered as significant.
Abbreviations: TPS, tumor proportion score; IHC, immunohistochemistry. | ||||||
EGFR (PCR) | 0.001* | < 0.001* | ||||
Mutation | 35 | 252 | 6 | 281 | ||
Negative | 35 | 106 | 15 | 126 | ||
ALK (IHC) | 0.008* | 0.039* | ||||
Positive | 5 | 6 | 2 | 9 | ||
Negative | 65 | 352 | 19 | 398 | ||
KRAS (PCR) | 0.096 | 0.006* | ||||
Mutation | 9 | 25 | 5 | 29 | ||
Negative | 61 | 333 | 16 | 378 | ||
ROS1 (PCR) | 0.416 | 0.140 | ||||
Rearrangement | 1 | 2 | 1 | 2 | ||
Negative | 69 | 356 | 20 | 405 |