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. 2019 Nov;16(4):811–821. doi: 10.20892/j.issn.2095-3941.2019.0209

2.

Correlation between PD-L1 expression and classical genomic aberrations in Chinese LADC patients

Genes alterations TPS ≥ 1% TPS < 1% P TPS ≥ 50% TPS < 50% P
*P< 0.05 was considered as significant.
Abbreviations: TPS, tumor proportion score; IHC, immunohistochemistry.
EGFR (PCR) 0.001* < 0.001*
 Mutation 35 252 6 281
 Negative 35 106 15 126
ALK (IHC) 0.008* 0.039*
 Positive 5 6 2 9
 Negative 65 352 19 398
KRAS (PCR) 0.096 0.006*
 Mutation 9 25 5 29
 Negative 61 333 16 378
ROS1 (PCR) 0.416 0.140
 Rearrangement 1 2 1 2
 Negative 69 356 20 405