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ZY4 kills bacteria by permeabilizing the cell membrane. After treatment with or without ZY4 for 30 min, the membrane morphology of P. aeruginosa CICC21625 (A) and A. baumannii 22933 (B) was determined by SEM. The arrows indicate the typical damage to the plasma membranes of the bacteria. Killing kinetics of ZY4 against P. aeruginosa (C) and A. baumannii (D). Data represent means ± SD of 3 individual experiments.
