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. 2019 Dec 5;13:429. doi: 10.3389/fnhum.2019.00429

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Copyright © 2019 Scarapicchia, Garcia-Barrera, MacDonald and Gawryluk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) An axial T2-FLAIR image of a prototypical participant from the control group (left) and associated probabilistic lesion volume map (right) generated by the LST-LPA. (B) An axial T2-FLAIR image of a prototypical participant with SCD (left) and associated probabilistic lesion volume map (right) generated by the LST-LPA. Prototypical SCD and healthy control participants were selected based on the proximity of their white matter (WM) lesion burden to their respective group means.