Distribution and viral RNA copy number in tissues of SFTSV-infected ferrets. Tissues (n = 3 per group) from ferrets infected with rHB29 (A), rHB29NSsP102A (B), rHB2912aaNSs (C), or CB8/2016 (D) were collected at days 4 (solid shapes) and 6 p.i. (open shapes), and viral RNA copy numbers were assessed with real-time PCR. Examined tissues included lung, liver, kidney, spleen, and intestine. The asterisks indicate significance compared to each day p.i. sample by the 2-tailed, unpaired t test (*P = 0.0195). Each experiment was performed for 3 biological and 3 technical repeats.