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. 2019 Dec 15;7(1):e000720. doi: 10.1136/bmjdrc-2019-000720

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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(A) Individual plasma activin A and (B) urine activin A/creatinine concentrations by log urine albumin-to-creatinine ratio (UACR) for Mayo (and Galway; plasma only) diabetes cohort. Estimated glomerular filtration rate (eGFR) group distribution is shown for each. Spearman’s correlations: log UACR with plasma activin A (r_s=0.48; p<0.0001) and log UACR with urine activin A/creatinine (r_s=0.65; p<0.0001) concentrations. Closed circle: eGFR ≥60 mL/min/1.73 m²; closed diamond: eGFR 45–59 mL/min/1.73 m²; open rectangle: eGFR 30–45 mL/min/1.73 m²; open triangle: eGFR ≤30 mL/min/1.73 m².