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. 2019 Dec 23;116(52):26173–26180. doi: 10.1073/pnas.1902299116

Fig. 3.

Fig. 3.

Cortical parcellations in 4 species. (A) Two mouse parcellations. (A1) A 41-area parcellation of isocortical (neocortical and transitional) cortex on a flattened, tangentially sectioned left hemisphere, based on multiple immunocytochemical markers. Adapted from ref. 27, with permission from Elsevier. (A2 and A3) Mouse parcellation (refs. 25 and 26; adapted with permission from ref. 26) displayed on a computationally flattened right hemisphere (A3) and mirror-flipped (A2) (symmetry assumed but not empirically demonstrated). Areal boundaries are based on numerous architectonic and immunocytochemical markers plus retinotopy using intrinsic optical imaging. Areas MOp and MOs differ in shape and relative size on the 2 flatmaps (red lines). (B1) Marmoset parcellation (28) is based on cytoarchitecture and multiple immunocytochemical markers. Adapted from ref. 28, with permission from Elsevier. (B2) Marmoset parcellation (29) is based on myelin, cytochrome oxidase, and calbindin markers. Adapted with permission from ref. 29, which is licensed under CC BY 4.0. The flatmap also shows tracer injection sites used for connectivity analyses. (C) Macaque cortical parcellations mapped to the Yerkes19 atlas. (C1) PHT00 parcellation (30) based on cytoarchitecture and SMI-32 immunocytochemistry. (C2) Composite multimodal parcellation (17) based on cytoarchitecture, myeloarchitecture, immunocytochemistry, and retinotopy. (C3) Architectonic parcellation (31) is based on cytoarchitecture and SMI-32 immunocytochemistry. (D1) A human unimodal parcellation (32) based on resting-state fMRI. Red arrows show pronounced asymmetric patterns in left vs. right hemispheres. (D2) The HCP_MMP1.0 multimodal parcellation (19) based on myelin maps, cortical thickness, resting-state fMRI, and visuotopic organization using rfMRI. Data for C and D are available at https://balsa.wustl.edu/9765g.