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Representative concentration–time curves for cisplatin a, carboplatin b, and oxaliplatin c. Solid lines are the platinum concentrations in plasma UF or CSF using standard sampling. Bars are the concentrations measured using microdialysis sampling over each time interval. For each drug, panel 1 is plasma UF and vein microdialysis, panel 2 is the muscle concentration using microdialysis, and panel 3 is CSF and brain microdialysis
