Table 3. Distribution of genotypic and allele frequency of gene polymorphism in filarial chyluria patients and controls.
Genotype/ Allele | Cases | Controls | OR | P-Value |
(n=186) (%) | (n=210) (%) | (95% CI) | ||
MBL2 codon 54: | ||||
Genotype | ||||
Wild (AA) | 107 (57.5) | 132 (62.9) | Ref | |
Hetero (AB) | 61 (32.8) | 64 (30.5) | 1.18 (0.76-1.81) | 0.464 |
Mutant (BB) | 18 (9.7) | 14 (6.7) | 1.59 (0.75 -3.34) | 0.224 |
AB+BB | 79 (42.5) | 78 (37.1) | 1.25 (0.84-1.87) | 0.279 |
MBL2 codon 54: | ||||
Allele | ||||
A | 275 (73.9) | 328 (78.1) | Ref | |
B | 97 (26.1) | 92 (21.9) | 1.26 (0.90 -1.74) | 0.169 |
MBL2-221: | ||||
Genotype | ||||
Wild (YY) | 95 (51.1) | 93 (44.3) | Ref | |
Hetero (YX) | 82 (44.1) | 84 (40.0) | 0.96 (0.63-1.45) | 0.831 |
Mutant (XX) | 9(4.8) | 33(15.7) | 0.27(0.12-0.59) | <0.001 |
YX+XX | 91 (48.9) | 117 (55.7) | 0.76 (0.51-1.13) | 0.177 |
MBL2-221: | ||||
Allele | ||||
Y | 272 (73.1) | 270 (64.3) | Ref | |
X | 100 (26.9) | 150 (35.7) | 0.66 (0.49-0.90) | 0.008 |