Table 3. Genotype and allele distributions of the six SNPs.
| THADA rs13429458 | p-value | ||||
| Genotype frequency | AA | AC | CC | ||
| PCOS (n=95) | 61 (64.2%) | 33 (34.7%) | 1 (1.1%) | 0.033* | |
| Control (n=94) | 74 (78.7%) | 18 (19.2%) | 2 (2.1%) | ||
| Total =189 | 135 (71.4%) | 51 (27%) | 3 (1.6%) | ||
| Allele frequency | A | C | |||
| PCOS (n=95) | 155 (81.6%) | 35 (18.4%) | |||
| Control (n=94) | 166 (88.3%) | 22 (11.7%) | |||
| TOX3rs4784165 | p-value | ||||
| Genotype frequency | GG | GT | TT | ||
| PCOS (n=94) | 12 (12.8%) | 35 (37.2%) | 47 (50%) | 0.606 | |
| Control (n=94) | 8 (8.5%) | 41 (43.6%) | 45 (47.9%) | ||
| Total =188 | 20 (10.6%) | 76 (40.4%) | 92 (48.9%) | ||
| Allele frequency | G | T | |||
| PCOS (n=95) | 59 (31.4%) | 129 (68.6 %) | |||
| Control (n=94) | 57 (30.3%) | 131 (69.7%) | |||
| FSHRrs2268361 | p-value | ||||
| Genotype frequency | CC | CT | TT | ||
| PCOS (n=95) | 22 (23.2%) | 47 (49.5%) | 26 (27.3%) | 0.339 | |
| Control (n=94) | 20 (21.3%) | 39 (41.5%) | 35 (37.2%) | ||
| Total =189 | 42 (22.2%) | 86 (45.5%) | 61 (32.3%) | ||
| Allele frequency | C | T | |||
| PCOS (n=95) | 91 (47.9%) | 99 (52.1%) | |||
| Control (n=94) | 79 (42%) | 109 (58%) | |||
| YAP1rs1894116 | p-value | ||||
| Genotype frequency | AA | AG | GG | ||
| PCOS (n=95) | 83 (87.3%) | 9 (9.5%) | 3 (3.2%) | 0.266 | |
| Control (n=94) | 78 (82.9%) | 15 (16%) | 1 (1.1%) | ||
| Total =189 | 161 (85.2%) | 24 (12.7%) | 4 (2.1%) | ||
| Allele frequency | A | G | |||
| PCOS (n=95) | 175 (92.1%) | 15 (7.9%) | |||
| Control (n=94) | 171 (91%) | 17 (9%) | |||
| RAB5Brs705702 | p-value | ||||
| Genotype frequency | AA | AG | GG | ||
| PCOS (n=95) | 70 (73.6%) | 22 (23.2%) | 3 (3.2%) | 0.641 | |
| Control (n=94) | 65 (69.2%) | 27 (28.7%) | 2 (2.1%) | ||
| Total =189 | 135 (71.4%) | 49 (25.9%) | 5 (2.6%) | ||
| Allele frequency | A | G | |||
| PCOS (n=95) | 162 (85.3%) | 28 (14.7%) | |||
| Control (n=94) | 157 (83.5%) | 31 (16.5%) | |||
| SNP | HMGA2rs2272046 | p-value | |||
| Genotype frequency | AA | AC | CC | ||
| PCOS (n=95) | 91 (95.8) | 4 (4.2%) | 0 (0%) | 0.414 | |
| Control (n=94) | 92 (97.9%) | 2 (2.1%) | 0 (0%) | ||
| Total =189 | 183 (96.8%) | 6 (3.2%) | 0 (0%) | ||
| Allele frequency | A | C | |||
| PCOS (n=95) | 186 (97.9%) | 4 (2.1%) | |||
| Control (n=94) | 186 (98.9%) | 2 (1.1%) | |||
| p-values were calculated by Pearson's chi-squared test. *p-values < 0.05 |