Table 5. Relationship between the six variants and AMH cutoff level in PCOS and control groups.
SNPs | Gene | Tested group | Genotype | Frequency | p-value |
AMH>3.19/ | |||||
AMH<3.19 | |||||
rs13429458 | THADA | PCOS | AA | 34/14 | 0.799 |
(n=79) | AC | 22/8 | |||
CC | Jan-00 | ||||
Control | AA | 18/36 | 0.321 | ||
(n=69) | AC | 12-Mar | |||
CC | 0/0 | ||||
rs4784165 | TOX3 | PCOS | GG | 4-Jun | 0.52 |
(n=78) | GT | 20/9 | |||
TT | 30/9 | ||||
Control | GG | 4-Jan | 0.498 | ||
(n=69) | GT | 18-Nov | |||
TT | 26-Sep | ||||
rs2268361 | FSHR | PCOS | CC | 13/5 | 0.293 |
(n=79) | CT | 27/14 | |||
TT | 17/3 | ||||
Control | CC | 11-Apr | 0.016* | ||
(n=69) | CT | 13/13 | |||
TT | 24-Apr | ||||
rs1894116 | YAP1 | PCOS | AA | 49/19 | 0.466 |
(n=79) | AG | 3-May | |||
GG | Mar-00 | ||||
Control | AA | 17/42 | 0.51 | ||
(n=69) | AG | 5-Apr | |||
GG | 0/1 | ||||
rs705702 | RAB5B | PCOS | AA | 43/16 | 0.298 |
(n=79) | AG | 13/4 | |||
GG | 2-Jan | ||||
Control | AA | 15/32 | 0.708 | ||
(n=69) | AG | 15-May | |||
GG | 1-Jan | ||||
rs2272046 | HMGA2 | PCOS | AA | 54/22 | 0.273 |
(n=79) | AC | Mar-00 | |||
CC | 0/0 | ||||
Control | AA | 21/47 | 0.505 | ||
(n=69) | AC | 0/1 | |||
CC | 0/0 | ||||
The p-values were calculated by chi-squared test. *p-values <0.05 |