Fig. 7.

Average percentage error in determining mutant allele frequency (MAF) for each intratumoral diversity model compared to the most accurate model as a reference for the stochastic model with the infinite-sites assumption (26, 32) (blue), and the deterministic model with (22) (red) and without (gold, this manuscript) the infinite-sites assumption (32). Because the x axis is on a log scale, the errors made by models with the infinite-sites assumption in estimating total tumor diversity in the high N(t) range on the Right of the graph is highly significant.