Table 2.

Mean number of mutations detected per nucleotide locus and associated variance

No.	Mean depth	Mean mutations per nucleotide	Variance in mutations per nucleotide	Variance/mean
1	1,783.71	1.6449E-03	1.6422E-03	0.9984
	19,453.23	1.4611E-02	1.8267E-02	1.2503
2	1,134.24	1.9355E-03	1.9318E-03	0.9981
	21,986.85	1.8484E-02	3.4788E-02	1.8820
3	2,131.11	1.2575E-03	1.2559E-03	0.9987
	20,897.13	1.2091E-02	1.4073E-02	1.1639
4	890.51	1.0647E-03	1.2571E-03	1.1808
	11,902.35	1.7809E-02	2.8525E-02	1.6018
5	1,285.00	1.2581E-03	1.2565E-03	0.9987
	16,433.63	9.5810E-03	1.6070E-02	1.6773

For low and high depth data points, left to right: the mean depth of sequencing, the mean number of mutations detected per nucleotide averaged across the DNA polymerase delta and epsilon capture set, the variance associated with the mean number of nucleotides, and the variance/mean ratio are given. The variance/mean ratio near 1 is characteristic of the Poisson distribution. Data for intermediate depths are similar.