Fig. 3.

Biological processes affected by genes changing over developmental time. Various modules are associated with different developmental time points and show a continuity of biological processes over time. The brown module is associated with E10.5 (early gut expressed genes) and the GO biological processes these genes are involved in include mostly transcription factors and chromatin modifiers. The salmon module associated with E12.5 contains genes involved in protein folding and transport which are also seen in the black and turquoise modules, which are associated with E14.5. The red and blue modules associated with E14.5 contain genes involved in the cell cycle, cell division, and DNA repair and are weakly expressed at this stage when compared to early developmental stages. The corresponding heat maps for all modules are also shown.