Table 2:

Divalent cations classification and effect on Ci-βγ unfolding.

	Tm2	Ti3	Ionic radius4	Classification5	MESPUES CN6	CSD CN7
Ca2+	94° C	82°C	100 pm	Hard	6–8	6, 7
Sr2+	91°C	79° C	118 pm	Hard	-	6, 8
Mn2+	84° C	72°C	83 pm8	Borderline	6	6
Mg2+	71°C	58°C	72 pm	Hard	6	6
Co2+	70° C	55°C	74.5pm9	Borderline	6	4, 6
Ni2+	61°C	50°C	69 pm	Borderline	4	4, 6
Zn2+	53°C	40°C	74 pm	Borderline	410	4
Apo	46° C	60°C	-	-	-