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. 2019 Dec 30;14(12):e0227091. doi: 10.1371/journal.pone.0227091

Table 3. Immunological profile for latent class phenotypes.

Healthy
mean ± SD
Early transient wheeze
mean ± SD
Current wheeze/asthma
mean ± SD
Mild asthma
mean ± SD
Moderate asthma
mean ± SD
Eosinophil granulocyte conc (cells x109/l) 0.25 ±0.23 0.30±0.36
β 0.04 (-0.03, 0.12)
0.25±0.21
β 0.00 (-0.08, 0.08)
0.33±0.30
β 0.08 (0.00, 0.16)
0.46±0.38
β 0.21 (0.12, 0.30)b
Lymphocyte particle conc (cells x109/l) 2.50 ±0.63 2.56±0.63
β 0.06 (-0.08, 0.19)
2.37±0.72
β -0.13 (-0.39, 0.12)
2.78±0.75
β 0.27 (0.06, 0.49)a
2.65±0.76
β 0.15 (-0.05, 0.35)
Neutrophil granulocyte conc (cells x109/l) 3.17±1.29 3.11±0.99
β -0.06 (-0.30, 0.17)
3.29±1.71
β 0.12 (-0.57, 0.81)
3.09±1.15
β -0.08 (-0.43, 0.26)
2.99±0.91
β -0.19 (-0.45, 0.07)

a p <0.05,

b p<0.0001

Beta coefficients with 95% confidence intervals compared to healthy phenotype.