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. 2019 Dec 30;14(12):e0226144. doi: 10.1371/journal.pone.0226144

Table 6. Logistic regression—Severe/hospitalized LRTI vs maternal psychosocial risk factors stratified by age.

0–3 monthsa 3–6 monthsb 6–9 monthsc 9–12 monthsd
Maternal psychosocial risk factor Adjusted OR (95% CI), p-value Adjusted OR (95% CI), p-value Adjusted OR (95% CI), p-value Adjusted OR (95% CI), p-value
Depression
Antenatal (n 1 = 994; n 2 = 936; n 3 = 994; n 4 = 994) 1.23 (0.74; 2.07), 0.425 2.55 (1.08; 6.01), 0.032 0.84 (0.28; 2.50), 0.760 1.16 (0.50; 2.69), 0.731
Postnatal—10 weeks (n 1 = 627; n 2 = 538; n 3 = 627; n 4 = 627) 1.29 (0.60; 2.79), 0.520 1.00 (0.24; 4.16), 0.996 1.99 (0.55; 7.14), 0.291 0.95 (0.30; 3.07), 0.936
Postnatal—6 months (n 1 = 579; n 2 = 546; n 3 = 579; n 4 = 536) 1.39 (0.62; 3.12), 0.431 0.93 (0.23; 3.76), 0.921 1.83 (0.42; 8.01), 0.424 0.30 (0.04; 2.46), 0.260
Postnatal—12 months (n 1 = 653; n 2 = 624; n 3 = 624; n 4 = 653) 2.46 (1.24; 4.87), 0.010 0.80 (0.21; 3.14), 0.752 1.80 (0.54; 5.97), 0.335 1.53 (0.51; 4.61), 0.448
Psychological distress
Antenatal (n 1 = 991; n 2 = 933; n 3 = 991; n 4 = 991) 1.44 (0.85; 2.45), 0.177 1.11 (0.42; 2.94), 0.829 1.22 (0.42; 3.54), 0.719 1.53 (0.66; 3.57), 0.325
Postnatal—10 weeks (n 1 = 628; n 2 = 539; n 3 = 628; n 4 = 628) 1.67 (0.68; 4.07), 0.260 3.33 (0.70; 15.93), 0.132 3.12 (0.79; 12.38), 0.106 1.12 (0.28; 4.52), 0.870
Postnatal—6 months(n 1 = 578; n 2 = 546; n 3 = 578; n 4 = 535) 3.01 (1.14; 7.96), 0.026 0.74 (0.13; 4.20), 0.737 1.27 (0.19; 8.55), 0.807 0.45 (0.05; 4.31), 0.491
Postnatal—12 months (n 1 = 684; n 2 = 652; n 3 = 652; n 4 = 684) 1.66 (0.68; 4.06), 0.270 1.57 (0.36; 6.78), 0.547 4.31 (1.04; 17.76), 0.043 0.75 (0.15; 3.70), 0.727
IPV
Antenatal (n 1 = 994; n 2 = 936; n 3 = 994; n 4 = 994) 0.92 (0.56; 1.51), 0.748 1.09 (0.46; 2.59), 0.851 1.04 (0.39; 2.78), 0.932 0.96 (0.43; 2.16), 0.920
Postnatal—10 weeks (n 1 = 628; n 2 = 539; n 3 = 628; n 4 = 628) 1.37 (0.69; 2.72), 0.367 3.63 (1.06; 12.40), 0.040 2.04 (0.58; 7.27), 0.269 0.82 (0.27; 2.45), 0.722
Postnatal—6 months (n 1 = 577; n 2 = 544; n 3 = 577; n 4 = 534) 2.28 (1.14; 4.60), 0.021 3.54 (1.08; 11.53), 0.036 0.63 (0.13; 3.04), 0.565 1.00 (0.31; 3.29), 0.997
Postnatal—12 months (n 1 = 675; n 2 = 644; n 3 = 644; n 4 = 675) 3.12 (1.71; 5.68), <0.001* 1.53 (0.52; 4.53), 0.440 1.04 (0.32; 3.36), 0.948 1.10 (0.44; 2.74), 0.846
Alcohol exposure
Antenatal (n 1 = 993; n 2 = 935; n 3 = 993; n 4 = 993) 2.95 (1.27; 6.84), 0.012 1.60 (0.34; 7.55), 0.550 1.87 (0.39; 9.01), 0.435 3.64 (1.10; 12.00), 0.034
Postnatal—10 weeks (n 1 = 625; n 2 = 536 n 3 = 625; n 4 = 625) 0.91 (0.23; 3.56), 0.887 1.40 (0.14; 14.11), 0.774 1.15 (0.12; 11.36), 0.902 0.43 (0.04; 4.43), 0.476
Postnatal—6 months (n 1 = 571; n 2 = 538; n 3 = 571; n 4 = 528) 0.76 (0.17; 3.47), 0.723 2.31 (0.46; 11.65), 0.310 1.67 (0.19; 15.03), 0.648 0.61 (0.07; 5.32), 0.656
Postnatal—12 months (n 1 = 583; n 2 = 556; n 3 = 556; n 4 = 556) 0.46 (0.14; 1.52), 0.202 1.85 (0.46; 7.48), 0.390 0.46 (0.05; 4.15), 0.493 0.75 (0.18; 3.14), 0.689

IPV, Intimate partner violence.

a-d Multiple logistic regression models adjusted for antenatal maternal psychosocial risk factor (in postnatal models); sex; recruitment site; HIV exposure; maternal education achievement; SES quartile; and LRTI in previous period

*Still significant if 1% significance level considered