Table 5. Association between DMR and DGE in neurons at 24 hours post injection.
Neurons | ||||
---|---|---|---|---|
Genomic feature | Gene symbol | DM logFC | DGE logFC | Gene description |
Upstream | ZBTB18 | 3,22 | -1,20 | Zinc finger and BTB domain-containing protein 18 |
SPP1 | -0,99 | 3,14 | Osteopontin | |
Promoter | SPP1 | -0,97 | 3,14 | Osteopontin |
PDE6B | -2,72 | 2,91 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | |
BTG2 | 5,23 | 1,49 | Protein BTG2 | |
DPYSL3 | 4,70 | 1,02 | Dihydropyrimidinase-related protein 3 | |
GADD45G | 4,59 | 2,54 | Growth arrest and DNA damage-inducible protein GADD45 gamma | |
SCRT2 | 3,77 | 1,43 | Transcriptional repressor scratch 2 | |
Exon | TRIB2 | 4,72 | 1,20 | Tribbles homolog 2 |
ZFP36 | 1,77 | 2,50 | mRNA decay activator protein ZFP36 | |
GAL | 2,13 | 3,64 | Galanin | |
CXCL12 | -0,87 | -1,96 | Stromal cell-derived factor 1 | |
SV2C | -1,27 | 2,56 | Synaptic vesicle glycoprotein 2C | |
GM5577 | 3,67 | -1,36 | Predicted gene 5577 | |
LTBP1 | -1,11 | 1,48 | Latent transforming growth factor beta binding protein 1 | |
ARL4D | -0,61 | 1,61 | ADP-ribosylation factor-like 4D | |
FNDC9 | -1,07 | 3,19 | Fibronectin type III domain-containing protein 9 | |
CD34 | 3,18 | -1,63 | Hematopoietic progenitor cell antigen CD34 | |
EPHX1 | 1,99 | -1,28 | Epoxide hydrolase 1 | |
TUBB6 | -0,51 | 1,49 | Tubulin beta-6 chain | |
BACH1 | -1,04 | 1,72 | Fanconi anemia group J protein homolog | |
Intron | SAMD11 | 0,73 | 2,19 | sterile alpha motif domain containing 11 |
KIF18A | 0,91 | 1,46 | Kinesin-like protein KIF18A | |
NPTX2 | -0,69 | 3,61 | Neuronal pentraxin-2 | |
IGF2BP2 | -0,56 | 2,04 | Insulin-like growth factor 2 mRNA-binding protein 2 | |
NPTX2 | -0,69 | 3,61 | Neuronal pentraxin-2 | |
Gene body | KIF18A | 0,80 | 1,46 | Kinesin family member 18A |
GAL | 2,09 | 3,64 | Galanin peptides | |
TRIB2 | 2,07 | 1,20 | tribbles pseudokinase 2 | |
SAMD11 | 0,70 | 2,19 | Sterile alpha motif domain-containing protein 11 | |
ADGRF4 | 0,92 | 1,66 | Adhesion G protein-coupled receptor F4 | |
LTBP1 | -0,52 | 1,48 | Latent-transforming growth factor beta-binding protein 1 | |
FAM129B | -0,59 | 1,40 | Niban-like protein 1 | |
IGF2BP2 | -0,54 | 2,04 | insulin-like growth factor 2 mRNA binding protein 2 | |
CD34 | 3,30 | -1,63 | CD34 antigen | |
SORCS3 | -0,40 | 2,28 | VPS10 domain-containing receptor SorCS3 | |
GXYLT2 | -0,85 | 1,40 | Glucoside xylosyltransferase 2 | |
SV2C | -0,63 | 2,56 | Synaptic vesicle glycoprotein 2C | |
ARL4D | -0,60 | 1,61 | ADP-ribosylation factor-like protein 4D | |
UTR3 | EGR3 | 3,45 | 1,61 | Early growth response protein 3 |
NEDD9 | -1,46 | 1,51 | Enhancer of filamentation 1 |
Genetic loci with coincidence of significant DM and DGE (FDR 0.25); logFC = log fold change.