Table 1. Comparison of elapid venom PLA2 activity and the time taken to cause 90% inhibition of nerve-mediated twitches (t90 values); N/A: Not available.
venom | PLA2 activity (μmol/min/mg) |
t90 at 3 μg/ml (min) |
t90 at 10 μg/ml (min) |
---|---|---|---|
B. candidus venom: Indonesia (BC-I) | 3041 ± 128 (n = 3) | 14.2 ± 0.5 (n = 4) | 8.8 ± 0.5 (n = 4) |
B. candidus venom: Malaysia (BC-M) | 3225 ± 233 (n = 3) | 36.0 ± 4.1 (n = 4) | 10.3 ± 0.5 (n = 4) |
B. candidus venom: Thailand (BC-T) | 5694 ± 815 (n = 3) | 22.0 ± 1.6 (n = 4) | 9.0 ± 1.4 (n = 4) |
B. fasciatus venom: Malaysia |
77.2 ± 4.9 (n = 3) [14] | N/A | 22.5 ± 5.0 (n = 3–4)[13] |
O. scutellatus venom: Australia |
N/A | 95.7 ± 8.7 (n = 4)[29] | 63.5 ± 5.7 (n = 4)[29] |
O. scutellatus venom: Papua New Guinea |
373.0 ± 32.6 (n = 3) [33] | N/A | 44.0 ± 5.0 (n = 4)[28] |
P. textilis venom: Australia |
N/A | 24.1 ± 1.7 (n = 4)[29] | 10.7 ± 1.1(n = 4)[29] |
Bee venom | 536 ± 16 (n = 3) | N/A | N/A |