Fig 4. Contributions of RpS12 to longevity and organ size.
A) Survival curve of female rpS12G97D flies compared to w11-18 (wild type) controls. Shown is the mean are 95% confidence limits from 3 replicates of 120 flies each. B) Survival curve of male rpS12G97D flies compared to w11-18 (wild type) controls. The difference is significant at p<0.0001 Log-rank (Mantel-Cox) test. See the S3 Fig for individual replicates and the S5 Table for raw data. C) Adult wing size was significantly smaller for the rpS12G97D females compared to w11-18 (p = 0.0165, two-tailed Welch’s t-test) and for rpS12G97D/- females compared to FRT80B (p = 0.000006, two-tailed Welch’s t-test). Wing size was also smaller for rpS12G97D/- males compared to FRT80B (p = 0.00014, two-tailed t-test) but not for rpS12G97D males compared to w11-18 (p = 0.126, two-tailed t-test). Raw data are tabulated in the S7 Table. D) Wings from rpS12G97D/- and FRT80B females overlaid to illustrate the difference. The rpS12G97D/- wing is smaller.