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. 2019 Dec 16;15(12):e1008530. doi: 10.1371/journal.pgen.1008530

Fig 7. 25(OH)D risk haplotypes affect skeletal parameters.

Fig 7

a) The individuals are grouped based on haplotype combination (AABB, AaBb or aabb), just as in Fig 6, but here only the individuals with pQCT measurements at 24-months are shown (n = 193). b) When combined, the ‘low 25(OH)D’ haplotypes from the two loci are strongly associated to all pQCT-parameters except for bone mineral content (total bone). When adjusting for the 25(OH)D concentration the association disappears or weakens considerably, suggesting that vitamin D is the mediator of the effect. (** p<0.01; *** p<0.001).