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Adverse events by randomization arm
| Adverse event grades | OLA-guided therapy | Standard of Care | p-value |
|---|---|---|---|
| Grade 1 – Mild | 5 (5%) | 2 (2%) | 0.44 |
| Grade 2 - Moderate | 27 (26%) | 24 (23%) | |
| Grade 3 – Severe | 36 (34%) | 29 (28%) | |
| Grade 4 – Life Threatening | 3 (3%) | 5 (5%) | |
| Grade 5 – Death | 34 (32%) | 43 (42%) |
Abbreviations: OLA, oligonucleotide ligation assay
