Table 5.

Trial registration data and protocol summary

Data category	Information
Primary registry and trial identifying number	ClinicalTrials.gov NCT03576898
Date of registration in primary registry	3 July 2018
Secondary identifying numbers
Source of monetary or material support	Francis I. Proctor Foundation, University of California, San Francisco
Contact for queries	John A. Gonzales, MD (john.gonzales@ucsf.edu)
Title	Systemic and Topical Antiviral Control of Cytomegalovirus Anterior uveitis: Treatment Outcomes
Countries of recruitment	Thailand, Taiwan, USA
Health condition or problem studied	Cytomegalovirus anterior uveitis treatment
Intervention(s)	Intervention: treating with 900 mg two times per day of oral valganciclovir, or topical 2% ganciclovir solution q2h for a duration of 28 days Control: placebo tablets and eyedrops
Key eligibility criteria	CMV positive anterior chamber paracentesis, active signs of anterior uveitis, no history of immunodeficiency, normal laboratory values for CBC and renal function
Study type	Competitive block randomised, placebo controlled clinical trial
Date of first enrolment	N/A
Target sample size	99 to 33 per treatment arm
Primary outcome	Change in log-transformed viral load
Key secondary outcomes	Objective and subjective time to achieve clinical quiescence, and the relationship of topical steroid strength and dosing on initial anterior chamber paracentesis quantitative viral load for CMV
Project timeline	July 2019–August 2021

CMV, cytomegalovirus.