Figure 3. Results of bromodomain-containing 4 (BRD4) chromatin immunoprecipitation with parallel sequencing (ChIP-Seq) in JVM-2 cells. A: Venn diagram showing the numbers of peaks detected by BRD4 ChIP-Seq when treated with either Control or I-BET151, an inhibitor of BRD4. B: Heatmaps of BRD4 signals between control and I-BET151-treated cells identified 2,890 promoters significantly affected by I-BET151. C: Gene tracks of BRD4 signals near the transcription start site of B-cell linker (BLNK), MYB, and paired box 5 (PAX5) genes in untreated (red) and IBET151- treated (blue) cells. Light blue bar indicates the region of a peak detected by the computational tool.