Figure 4. a, b.

Taxonomic analysis at the species level (microbiomes showing a significant difference in each group). Fifteen species with more than 1% in each group are listed in order. (a) Dolosigranulum pigrum, Megasphaera micronuciformis, Clostridium disporicum, and Stomatobaculum longum were significantly higher in the OME group than in the control group. However, Dolosigranulum pigrum was the only species with more than 1% composition. (b) Of the 51 species that were significantly higher in the control group, five species (Loriellopsis cavernicola, Burkholderia plantarii, Pantoea deleyi, Curtobacterium albidum, and Xanthomonas theicola) showed more than 1% composition on average (*p<0.05, **p<0.01).

OME: otitis media with effusion.