Figure 4.
btrS dampens the host adaptive response. Number of CD4+ T cells (A), CD8+ T cells (B), and B cells (C) in the lungs of mice at day 14 post-infection with B. bronchiseptica RB50 (blue), RB50ΔbtrS (red) or naïve control (grey). Anti-B. bronchiseptica IgG antibody titers (D) at day 10 post-infection (4–6 mice per group, n = 5). Statistical significance was calculated using Two-Way ANOVA. *p < 0.05, **p < 0.005, ***p < 0.0005, and ****p < 0.0001. Error bars indicate SEM, ND stands for Not Detected.