Fig. 2.

Analysis of the effect of antiretroviral drugs treatment on HERVs and cancer stem cell-associated genes expression depending on microenvironmental changes. Relative expression of HERV-K, HERV-H, CD133 and embryonic transcription factors (OCT4, NANOG, SOX2) analyzed by Real-time PCR, in TVM-A12, HepG2 and A549 cells treated with antiretroviral drugs in SM or X-VIVO. Data are shown as mean ± SE of at least three experiments performed. (*) p ≤ 0.050 or (**) p < 0.001. Black asterisks represent comparisons to the untreated control in SM. Red asterisks represent comparisons to the untreated control in X-VIVO