Skip to main content
. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Pharm Sci. 2019 Aug 10;109(1):191–205. doi: 10.1016/j.xphs.2019.08.005

Table 5:

Effect of disease or exercise on various lymph flows

Lymph flow Rate of lymph flow Species Disease/exercise Reference
Thoracic duct lymph flow 1 mL/min Humans Healthy Dumont et al. 119
Thoracic duct lymph flow 3–6-fold higher than healthy Humans Cirrhosis Dumont et al. 119
Thoracic duct lymph flow 1.5 mL/min Pigs Normal Malbrain et al.120
Thoracic duct lymph flow 2-fold than healthy Pigs IV LPS administration Malbrain et al.120
Nodal lymph flow 1.49 mL/gm/min Rats Normal DSouza et al.121
Nodal lymph flow 0.5 mL/gm/min Rats Cancer cell injected lymph nodes DSouza et al.121
Pre-nodal lymph flow 13.2 mL/24 h Humans Healthy Olszewski et al.103
Pre-nodal lymph flow 22.6 mL/24 h Humans Rheumatoid arthritis patients Olszewski et al.103
Thoracic duct lymph flow 1.7 mL/min Dogs Normal Desai et al.122
Thoracic duct lymph flow 3.9 mL/min Dogs 1.5 miles/h on treadmill Desai et al.122
Thoracic duct lymph flow 9 mL/min Dogs 10 miles/h on treadmill Desai et al.122