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. 2019 Nov 28;79(1):164–166. doi: 10.1136/annrheumdis-2019-216044

Table 1.

Association analysis of OAT10/SLC22A13 variant, rs117371763 [Arg377Cys (R377C)], with gout susceptibility

Gout cases Controls p value OR (95% CI)
C/C C/T T/T MAF (%) C/C C/T T/T MAF (%)
Discovery phase 447 31 2 3.65 427 46 6 6.05 0.014 0.59 (0.38 to 0.90)
Replication phase 859 63 2 3.63 1900 203 5 5.02 0.015 0.71 (0.53 to 0.94)
Meta-analysis 7.8×10-4 0.67 (0.53 to 0.85)

In the meta-analysis, no apparent heterogeneity was observed (p value for Cochran's Q test=0.48, I2=0%).

MAF, minor allele frequency.