Table 1.
Comparison of indicators between the good prognosis group and poor prognosis group before treatment
| Good prognosis group (n = 274) | Poor prognosis group (n = 81) | t/χ2 value | P value | |
| Age | 53.64 ± 15.38 | 60.47 ± 8.34 | 3.831 | 0.000 |
| Gender (Male/Female) | 143/131 | 43/38 | 0.020 | 0.887 |
| BMI (kg/m2) | 26.49 ± 5.34 | 25.39 ± 5.91 | 1.589 | 0.113 |
| Smoking [n (%)] | 74 (27.01%) | 24 (29.63%) | 0.215 | 0.643 |
| History of alcohol abuse [n (%)] | 39 (14.23%) | 13 (16.05%) | 0.165 | 0.685 |
| Family history [n (%)] | 46 (16.79%) | 20 (24.69%) | 2.580 | 0.108 |
| Tumor diameter (cm) | 2.08 ± 1.47 | 5.69 ± 2.54 | 16.125 | 0.000 |
| Tumor location | ||||
| Ascending colon [n (%)] | 39 | 13 | 3.139 | 0.535 |
| Transverse colon [n (%)] | 14 | 7 | ||
| Lower colon [n (%)] | 25 | 10 | ||
| Sigmoid colon [n (%)] | 84 | 22 | ||
| Rectum [n (%)] | 112 | 29 | ||
| Tumor histology type | ||||
| Adenocarcinoma | 177 | 53 | 0.019 | 0.890 |
| Mucinous adenocarcinoma and signet ring cell carcinoma | 97 | 28 | ||
| TNM stage | ||||
| I | 10 (3.65%) | 6 (7.41%) | 29.292 | 0.000 |
| II | 213 (77.74%) | 38 (46.91%) | ||
| III | 30 (10.95%) | 24 (29.63%) | ||
| IV | 21 (7.66%) | 13 (16.05%) | ||
| Dukes stage | ||||
| A | 17 (6.20%) | 1 (1.23%) | 0.062 | |
| B | 177 (64.60%) | 48 (59.26%) | ||
| C | 80 (29.20%) | 32 (39.51%) | ||
| PCNA | ||||
| 1 | 98 | 4 | 114.291 | 0.000 |
| 2 | 122 | 11 | ||
| 3 | 45 | 43 | ||
| 4 | 9 | 23 | ||
| P53 | ||||
| - | 34 | 11 | 4.908 | 0.297 |
| + | 64 | 14 | ||
| ++ | 61 | 17 | ||
| +++ | 78 | 23 | ||
| ++++ | 37 | 19 | ||
| GPS | ||||
| 0 | 233 (85.04%) | 9 (11.11%) | 157.579 | 0.000 |
| 1 | 24 (8.76%) | 40 (49.38%) | ||
| 2 | 17 (6.20%) | 32 (39.51%) | ||
| C-reactive protein (mg/L) | 2.73 ± 0.64 | 21.83 ± 16.34 | 19.364 | 0.000 |
| Albumin (g/L) | 42.43 ± 7.93 | 33.74 ± 6.21 | 9.071 | 0.000 |
| WBC count (9 × 103/mm3) | 5.89 ± 1.98 | 8.53 ± 2.83 | 9.481 | 0.000 |
| Platelet count (9 × 104/mm3) | 237.43 ± 103.28 | 247.23 ± 116.39 | 0.728 | 0.467 |
| NLR | 2.68 ± 1.73 | 4.53 ± 3.29 | 6.699 | 0.000 |
| CAR | 0.089 ± 0.017 | 0.175 ± 0.092 | 14.693 | 0.000 |
| D-dimer (μg/mL) | 0.553 ± 0.207 | 0.943 ± 0.375 | 13.117 | 0.000 |
| Fibrinogen (g/L) | 3.121 ± 1.542 | 3.524 ± 1.053 | 2.204 | 0.028 |
| CEA (ng/mL) | 3.34 ± 1.82 | 6.13 ± 2.36 | 11.281 | 0.000 |
| CA199 (U/mL) | 186.82 ± 139.74 | 635.24 ± 284.38 | 15.067 | 0.000 |
BMI: Body mass index; TNM: Tumor-node-metastasis; PCNA: Proliferating cell nuclear antigen; GPS: Glasgow prognostic score; WBC: White blood cell; NLR: Neutrophil-lymphocyte ratio; CAR: C-reactive protein/albumin ratio; CEA: Carcinoembryonic antigen; CA199: Carbohydrate antigen 199.