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. 2019 Dec 10;93(24):e2294–e2305. doi: 10.1212/WNL.0000000000008620

Figure 3. CSF analysis pretransplantation (V5) and 2 weeks post-transplantation (V6).

Figure 3

(A) A significant increase in vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), and leukemia inhibitory factor (LIF) levels is shown in the CSF of the mesenchymal stem cell (MSC)-neurotrophic factor (NTF) cells treated group (upper panels) with no detectable change in the placebo group (lower panels). (B) A significant decrease in monocyte chemoattractant protein-1 (MCP-1), stromal cell-derived factor-1a (SDF-1), and chitotriosidase-1 (CHIT-1) levels is shown in the CSF of the MSC-NTF cells treated group (upper panels) with no significant change in the placebo group (lower panels). *p < 0.05, **p < 0.01, ***p < 0.001.